Iophenoxic Acid

Iophenoxic Acid

SCHEMBL966564

CCC(Cc1c(I)cc(I)c(O)c1I)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 1.00
CYP2C9 P11712 3/20 0.71
LMNA P02545 3/20 0.71
CYP1A2 P05177 3/20 0.71
HIF1A Q16665 2/20 0.71
TBXA2R P21731 2/20 0.71
CHRM1 P11229 1/20 0.71
PDE4A P27815 1/20 0.71
ADRA1A P35348 1/20 0.71
SIRT5 Q9NXA8 1/20 0.44
CYP2C19 P33261 1/20 0.38
MEN1 O00255 4/20 0.36
KMT2A Q03164 4/20 0.36
PPARG P37231 4/20 0.36
THRB P10828 3/20 0.36
TTR P02766 2/20 0.36
ADORA3 P0DMS8 2/20 0.36
PDE4D Q08499 2/20 0.36
HSD17B10 Q99714 2/20 0.36
NR1I2 O75469 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25478285 0.84 TDP1 (0.72) TDP1CYP2C9LMNACYP1A2HIF1A
Iopanoic Acid SCHEMBL38976 0.83 LMNA (1.00) TDP1CYP2C9LMNACYP1A2HIF1A
Iopanoic Acid SCHEMBL29358912 0.83 LMNA (1.00) TDP1CYP2C9LMNACYP1A2HIF1A
SCHEMBL19379584 0.82 TDP1 (0.69) TDP1CYP2C9LMNACYP1A2HIF1A
SCHEMBL10495750 0.81 CYP1A2 (0.70) TDP1CYP2C9LMNACYP1A2HIF1A
SCHEMBL19678558 0.80 TDP1 (0.67) TDP1CYP2C9LMNACYP1A2HIF1A
SCHEMBL22097447 0.80 TDP1 (0.67) TDP1CYP2C9LMNACYP1A2HIF1A
SCHEMBL3866615 0.80 TDP1 (0.67) TDP1CYP2C9LMNACYP1A2HIF1A
SCHEMBL11373524 0.80 TDP1 (0.66) TDP1CYP2C9LMNACYP1A2HIF1A
SCHEMBL19260214 0.79 TDP1 (0.64) TDP1CYP2C9LMNACYP1A2HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 411 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260124313-A1 SITE-SPECIFIC COVALENT LIGATION OF HUMAN SERUM ALBUMIN UNIV CALIFORNIA (US) 2026-05-07 US claimed
EP-4656211-A2 COMPOSITIONS FOR EMBOLIZATION Iberhospitex, S.A. (ES) 2025-12-03 EP claimed
EP-4376905-B1 COMPOSITIONS FOR EMBOLIZATION IBERHOSPITEX SA (ES) 2025-10-22 EP claimed
US-20240358885-A1 COMPOSITIONS FOR EMBOLIZATION IBERHOSPITEX, S.A. (ES) 2024-10-31 US claimed
EP-4376905-A1 COMPOSITIONS FOR EMBOLIZATION Iberhospitex, S.A. (ES) 2024-06-05 EP claimed
WO-2024077212-A2 SITE-SPECIFIC COVALENT LIGATION OF HUMAN SERUM ALBUMIN THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-04-11 WO claimed
WO-2023006679-A1 COMPOSITIONS FOR EMBOLIZATION IBERHOSPITEX, S.A. (ES) 2023-02-02 WO claimed
US-20220313171-A1 Imaging and Treatment Methods for Early Detection of Diseases ALGBURI ISHTAR FAISAL (CA) 2022-10-06 US claimed
US-20210069352-A1 IODINE-BASED PARTICLES NANOPROBES, INC. 2021-03-11 US claimed
CN-109916691-A Reagent for cellular esterases dyeing 迈克生物股份有限公司 2019-06-21 CN claimed
US-6281515-B1 Lightweight radiation protective garments MERIDIAN RESEARCH AND DEVELOPMENT 2001-08-28 US claimed
WO-2000034957-A1 LIGHTWEIGHT RADIATION PROTECTIVE GARMENTS MERIDIAN RESEARCH AND DEVELOPMENT (US) 2000-06-15 WO claimed
CN-1179081-A Osmolyte regulator TALL HOLDINGS PTY LTD AB (AU) 1998-04-15 CN claimed
CN-1034216-C 7-(substituted)-9-[(substituted glycyl) amido]-6-demethyl-6-deoxytetracyclines AMERICAN CYANAMID CO (US) 1997-03-12 CN claimed
CN-1033971-C 9-[(substituted glycyl) amido]-6-demethyl-6-deoxytetracyclines AMERICAN CYANAMID CO (US) 1997-02-05 CN claimed
CN-1033087-C Novel 7-(substituted)-8-(substituted-9-[(substituted glycyl) amido]-6-demethyl-6-deoxytetracyclines AMERICAN CYANAMID CO (US) 1996-10-23 CN claimed
CN-1087899-A The 9-[(substituted glycyl) amido)]-6-demethyl-6-deoxidation tsiklomitsin AMERICAN CYANAMID CO (US) 1994-06-15 CN claimed
CN-1087626-A The glycyl that novel 7-(replacement)-8-(replacement)-9-[(replaces) amido]-6-demethyl-6-deoxidation tsiklomitsin AMERICAN CYANAMID CO (US) 1994-06-08 CN claimed
CN-1083805-A 7-(replacement)-9-[(substituted glycyl) amido]-6-demethylation-6-deoxytetra cycline AMERICAN CYANAMID CO (US) 1994-03-16 CN claimed
US-4192859-A MEDICAL DIAGNOSIS USING X-RAYS E. R. SQUIBB & SONS, INC. (US) 1980-03-11 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260124313-A1 SITE-SPECIFIC COVALENT LIGATION OF HUMAN SERUM ALBUMIN GLP1R, ALB, GIPR TDP1 2366/4885CYP2C9 3499/4885LMNA 1893/4885
US-20210069352-A1 IODINE-BASED PARTICLES TPO, BRI3BP, INSRR TDP1 3189/4885CYP2C9 4171/4885LMNA 3921/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.