Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 7/20 | 0.41 |
| ▸ | MMP3 | P08254 | 6/20 | 0.41 |
| ▸ | MMP9 | P14780 | 6/20 | 0.41 |
| ▸ | MMP2 | P08253 | 5/20 | 0.41 |
| ▸ | MMP8 | P22894 | 5/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 4/20 | 0.37 |
| ▸ | MMP7 | P09237 | 3/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12468859 | 0.80 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNAPOLBMMP13MMP3 | |
| SCHEMBL12468609 | 0.80 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNAPOLBMMP13MMP3 | |
| SCHEMBL2361594 | 0.80 | LMNA (0.49) | SMN1; SMN2LMNAPOLBMMP13MMP3 | |
| SCHEMBL30543794 | 0.78 | LMNA (0.48) | SMN1; SMN2LMNAPOLBMMP13MMP3 | |
| SCHEMBL29850834 | 0.77 | LMNA (0.56) | SMN1; SMN2LMNAPOLBMMP13MMP3 | |
| SCHEMBL29429485 | 0.77 | LMNA (0.47) | SMN1; SMN2LMNAPOLBMMP13MMP3 | |
| SCHEMBL2360585 | 0.77 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNAPOLBMMP13MMP3 | |
| SCHEMBL31131213 | 0.77 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNAPOLBMMP13MMP3 | |
| SCHEMBL9022812 | 0.77 | GPR119 (0.45) | MMP13MMP3MMP9MMP2MMP8 | |
| SCHEMBL29356156 | 0.76 | LMNA (0.46) | SMN1; SMN2LMNAPOLBMMP13MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0500835-A1 | A NOVEL QUINOLONE CARBOXYLIC ACID DERIVATIVE. | DAE WOONG PHARMA (KR) | 1992-09-02 | — | — | EP | disclosed |
| WO-1992004342-A1 | A NOVEL QUINOLONE CARBOXYLIC ACID DERIVATIVE | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 1992-03-19 | — | — | WO | disclosed |