Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 4/20 | 0.67 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.58 |
| ▸ | ACACA | Q13085 | 1/20 | 0.57 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9474891 | 0.89 | ACACB (0.65) | ACACBALOX5ACACANPY5RLTA4H | |
| SCHEMBL9685836 | 0.82 | ACACB (0.66) | ACACBALOX5ACACALTA4H | |
| SCHEMBL9668698 | 0.80 | ACACB (0.63) | ACACBALOX5ACACALTA4H | |
| SCHEMBL9473341 | 0.79 | ALOX5 (0.75) | ACACBALOX5NPY5RLTA4H | |
| SCHEMBL9398051 | 0.78 | ACACB (0.60) | ACACBALOX5LTA4HMAOB | |
| SCHEMBL9707244 | 0.77 | ALOX5 (0.66) | ALOX5SMN1; SMN2MAOB | |
| SCHEMBL3425496 | 0.77 | ACACB (0.64) | ACACBALOX5ACACALTA4HNPC1 | |
| SCHEMBL10619656 | 0.77 | ALOX5 (0.73) | ACACBALOX5 | |
| SCHEMBL9668706 | 0.77 | ALOX5 (0.62) | ACACBALOX5NPY5RLTA4HMAOB | |
| SCHEMBL10618997 | 0.77 | ALOX5 (0.73) | ACACBALOX5NPY5RLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175183-A | Antiinflammatory agents, respiratory system disorders | ABBOTT LABORATORIES (US) | 1992-12-29 | — | — | US | disclosed |
| WO-1990008545-A1 | LIPOXYGENASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1990-08-09 | — | — | WO | disclosed |