Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 1/20 | 0.38 |
| ▸ | ARG2 | P78540 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.36 |
| ▸ | PRCP | P42785 | 2/20 | 0.35 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.35 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9669068 | 0.91 | MEN1 (0.38) | PRCPGABBR2GABBR1LMNACYP2C9 | |
| SCHEMBL9669064 | 0.85 | CYP2C9 (0.40) | PRCPGABBR2GABBR1LMNACYP2C9 | |
| SCHEMBL9667737 | 0.81 | CYP2C9 (0.39) | PRCPGABBR2GABBR1LMNACYP2C9 | |
| SCHEMBL9777050 | 0.77 | CYP2C9 (0.36) | PRCPGABBR2GABBR1LMNACYP2C9 | |
| SCHEMBL9668129 | 0.77 | CYP2C9 (0.36) | PRCPGABBR2GABBR1LMNACYP2C9 | |
| SCHEMBL9669215 | 0.77 | CYP2C9 (0.38) | PRCPGABBR2GABBR1LMNACYP2C9 | |
| SCHEMBL9668337 | 0.77 | ALDH1A1 (0.36) | LMNA | |
| SCHEMBL9668295 | 0.76 | FFAR2 (0.41) | PRCPGABBR2GABBR1LMNACYP2C9 | |
| SCHEMBL9669142 | 0.71 | ALDH1A1 (0.38) | LMNACYP2C9CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL9669099 | 0.70 | LMNA (0.43) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0293351-B1 | NEW ARALKYL ESTERS AND PROCESSES FOR THEIR PREPARATION | AKTIEBOLAGET ASTRA (SE) | 1992-03-25 | — | — | EP | disclosed |
| US-4990534-A | Aralkyl esters and processes for their preparation | AKTIEBOLAGET ASTRA (SE) | 1991-02-05 | — | — | US | disclosed |
| EP-0362264-A1 | NEW ARALKYL ESTERS AND PROCESSES FOR THEIR PREPARATION | AKTIEBOLAGET ASTRA (SE) | 1990-04-11 | — | — | EP | disclosed |
| WO-1988009327-A1 | NEW ARALKYL ESTERS AND PROCESSES FOR THEIR PREPARATION | AKTIEBOLAGET ASTRA (SE) | 1988-12-01 | — | — | WO | disclosed |
| EP-0293351-A2 | New aralkyl esters and processes for their preparation | AKTIEBOLAGET ASTRA (SE) | 1988-11-30 | — | — | EP | disclosed |