Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 4/20 | 0.36 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.36 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9669064 | 0.83 | CYP2C9 (0.40) | CYP2C9GABBR2GABBR1LMNACYP2D6 | |
| SCHEMBL9667737 | 0.82 | CYP2C9 (0.39) | CYP2C9GABBR2GABBR1LMNACYP2D6 | |
| SCHEMBL9669068 | 0.81 | MEN1 (0.38) | CYP2C9GABBR2GABBR1LMNACYP2D6 | |
| SCHEMBL9777050 | 0.78 | CYP2C9 (0.36) | CYP2C9GABBR2GABBR1LMNACYP2D6 | |
| SCHEMBL9669164 | 0.77 | ARG1 (0.38) | CYP2C9GABBR2GABBR1LMNACYP2D6 | |
| SCHEMBL9668295 | 0.74 | FFAR2 (0.41) | CYP2C9GABBR2GABBR1LMNACYP2D6 | |
| SCHEMBL9669215 | 0.72 | CYP2C9 (0.38) | CYP2C9GABBR2GABBR1LMNACYP2D6 | |
| SCHEMBL9669142 | 0.69 | ALDH1A1 (0.38) | CYP2C9LMNACYP2D6CYP2C19CYP3A4 | |
| SCHEMBL9669099 | 0.69 | LMNA (0.43) | CYP2C9LMNACYP2C19MEN1KMT2A | |
| SCHEMBL9669476 | 0.68 | GRM2 (0.37) | AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0293351-B1 | NEW ARALKYL ESTERS AND PROCESSES FOR THEIR PREPARATION | AKTIEBOLAGET ASTRA (SE) | 1992-03-25 | — | — | EP | disclosed |
| US-4990534-A | Aralkyl esters and processes for their preparation | AKTIEBOLAGET ASTRA (SE) | 1991-02-05 | — | — | US | disclosed |
| EP-0362264-A1 | NEW ARALKYL ESTERS AND PROCESSES FOR THEIR PREPARATION | AKTIEBOLAGET ASTRA (SE) | 1990-04-11 | — | — | EP | disclosed |
| WO-1988009327-A1 | NEW ARALKYL ESTERS AND PROCESSES FOR THEIR PREPARATION | AKTIEBOLAGET ASTRA (SE) | 1988-12-01 | — | — | WO | disclosed |
| EP-0293351-A2 | New aralkyl esters and processes for their preparation | AKTIEBOLAGET ASTRA (SE) | 1988-11-30 | — | — | EP | disclosed |