Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | RORB | Q92753 | 6/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8692246 | 0.87 | RECQL (0.53) | ALDH1A1LMNAGAARECQLRORB | |
| SCHEMBL8118710 | 0.81 | RECQL (0.57) | ALDH1A1LMNAGAARECQLRORB | |
| SCHEMBL8690167 | 0.81 | ALDH1A1 (0.50) | ALDH1A1LMNAGAARECQLKDM4E | |
| SCHEMBL11640868 | 0.79 | RECQL (0.54) | ALDH1A1LMNAGAARECQLRORB | |
| SCHEMBL9039352 | 0.78 | LMNA (0.67) | ALDH1A1LMNAGAARECQLRORB | |
| SCHEMBL14235181 | 0.75 | ALDH1A1 (0.51) | ALDH1A1LMNAGAARECQLRORB | |
| SCHEMBL9042066 | 0.75 | RECQL (0.50) | ALDH1A1LMNAGAARECQLRORB | |
| SCHEMBL9654311 | 0.75 | RAB9A (0.47) | ALDH1A1LMNAGAAPOLBKDM4E | |
| SCHEMBL9042068 | 0.74 | LMNA (0.49) | ALDH1A1LMNAGAARECQLRORB | |
| SCHEMBL9674528 | 0.74 | RECQL (0.49) | ALDH1A1LMNAGAARECQLRORB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230942-B1 | THIENO-1,4-DIAZEPINES | BOEHRINGER INGELHEIM KG (DE) | 1992-04-29 | — | — | EP | disclosed |
| US-4900729-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | BOEHRINGER INGELHEIM KG (DE) | 1990-02-13 | — | — | US | disclosed |
| EP-0230942-A2 | Thieno-1,4-diazepines | BOEHRINGER INGELHEIM KG (DE) | 1987-08-05 | — | — | EP | disclosed |