Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 11/20 | 0.55 |
| ▸ | HTR1A | P08908 | 6/20 | 0.52 |
| ▸ | DRD2 | P14416 | 6/20 | 0.52 |
| ▸ | HTR2A | P28223 | 6/20 | 0.52 |
| ▸ | HTR6 | P50406 | 6/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9131045 | 0.85 | HTR7 (0.58) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL9132098 | 0.84 | HTR7 (0.67) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL9134836 | 0.84 | DRD2 (0.52) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL9132141 | 0.83 | DRD2 (0.53) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL9134164 | 0.83 | HTR7 (0.55) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL9132055 | 0.82 | HTR7 (0.65) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL9131309 | 0.82 | HTR1A (0.51) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL9131067 | 0.79 | HTR7 (0.50) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL9134839 | 0.78 | ADRA1D (0.42) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL9131080 | 0.78 | HTR7 (0.59) | HTR7HTR1ADRD2HTR2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0338331-B1 | 1,3 DISUBSTITUTED PYRROLIDINES | BAYER AG (DE) | 1992-10-21 | — | — | EP | disclosed |
| EP-0338331-A1 | 1,3 Disubstituted Pyrrolidines | BAYER AG (DE) | 1989-10-25 | — | — | EP | disclosed |