Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | CMA1 | P23946 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9670650 | 0.83 | FAAH (0.40) | — | |
| SCHEMBL9670225 | 0.82 | GLS (0.36) | — | |
| SCHEMBL9671106 | 0.80 | ACACB (0.33) | — | |
| SCHEMBL9669952 | 0.80 | HRH1 (0.37) | KDM4EKMT2A | |
| SCHEMBL9670642 | 0.79 | MMP12 (0.37) | KMT2A | |
| SCHEMBL9671319 | 0.79 | NPC1 (0.35) | L3MBTL1 | |
| Benzene SCHEMBL9326381 | 0.79 | ALDH1A1 (0.36) | — | |
| SCHEMBL9325034 | 0.79 | GLS2 (0.35) | — | |
| SCHEMBL9670950 | 0.79 | GLS2 (0.35) | — | |
| SCHEMBL7295059 | 0.79 | GLS2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4780405-A | Carbonic anhydrase inhibitor-tagged nucleic acid probes | SISKA DIAGNOSTICS, INC. (US) | 1988-10-25 | — | — | US | claimed |
| EP-0295056-B1 | ANTI-INFLAMMATORY FURANONES | ALLERGAN, INC (US) | 1992-08-05 | — | — | EP | disclosed |
| US-5134128-A | Immunosuppressive and antiproliferative activity for psoriasis and calcium homeostasis | ALLERGAN, INC. (US) | 1992-07-28 | — | — | US | disclosed |
| EP-0295056-A1 | Anti-inflammatory furanones | ALLERGAN, INC (US) | 1988-12-14 | — | — | EP | disclosed |