Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL294867 | 0.88 | PPM1B (0.42) | ALDH1A1HCAR2EPHX2 | |
| SCHEMBL19658928 | 0.85 | ALDH1A1 (0.44) | ALDH1A1ATMTSHRHPGDHCAR2 | |
| SCHEMBL10836923 | 0.85 | ACHE (0.32) | — | |
| SCHEMBL10835432 | 0.83 | ALDH1A1 (0.45) | ALDH1A1TSHRLMNASMN1; SMN2 | |
| SCHEMBL10835159 | 0.83 | EPHX2 (0.31) | EPHX2 | |
| SCHEMBL1593042 | 0.83 | ALDH1A1 (0.45) | ALDH1A1ATMTSHRHPGDHCAR2 | |
| SCHEMBL1577887 | 0.80 | ALDH1A1 (0.42) | ALDH1A1ATMTSHRHPGDHCAR2 | |
| SCHEMBL294716 | 0.79 | LMNA (0.43) | ALDH1A1HPGDLMNA | |
| SCHEMBL12497183 | 0.79 | ALDH1A1 (0.41) | ALDH1A1ATMTSHRHPGDHCAR2 | |
| SCHEMBL5314830 | 0.78 | CHRNB2 (0.31) | ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470295-A1 | Process for the preparation of 2,2-dimethylcyclopropane-carboxylic acid butyl ester and its corresponding amide | HÜLS AKTIENGESELLSCHAFT (DE) | 1992-02-12 | — | — | EP | disclosed |
| EP-0470295-A1 | Process for the preparation of 2,2-dimethylcyclopropane-carboxylic acid butyl ester and its corresponding amide | HÜLS AKTIENGESELLSCHAFT (DE) | 1992-02-12 | — | — | EP | disclosed |