Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4105383 | 0.83 | ALDH1A1 (0.52) | ALDH1A1MAPTMEN1KMT2ARXFP1 | |
| SCHEMBL3227136 | 0.78 | MAPT (0.72) | ALDH1A1MAPTMEN1KMT2ARXFP1 | |
| SCHEMBL10744154 | 0.78 | MMP2 (0.50) | ALDH1A1MAPTMEN1KMT2ARXFP1 | |
| SCHEMBL9770587 | 0.77 | KDM4E (0.49) | ALDH1A1MAPTMEN1KMT2ARXFP1 | |
| SCHEMBL10747756 | 0.77 | ALDH1A1 (0.48) | ALDH1A1MAPTMEN1KMT2ARXFP1 | |
| SCHEMBL9673214 | 0.74 | ALDH1A1 (0.55) | ALDH1A1MAPTMEN1KMT2ARXFP1 | |
| SCHEMBL10748287 | 0.74 | MMP12 (0.48) | ALDH1A1MAPTMEN1KMT2ARXFP1 | |
| SCHEMBL10748109 | 0.73 | MAPT (0.54) | ALDH1A1MAPTMEN1KMT2ARXFP1 | |
| SCHEMBL10746820 | 0.73 | KDM4E (0.53) | ALDH1A1MAPTMEN1KMT2ARXFP1 | |
| SCHEMBL10748498 | 0.72 | ALDH1A1 (0.53) | ALDH1A1MAPTMEN1KMT2ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0190265-B1 | PYRIDONE ESTERS AS INOTROPIC AGENTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1992-01-08 | — | — | EP | claimed |
| EP-0190265-B1 | PYRIDONE ESTERS AS INOTROPIC AGENTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1992-01-08 | — | — | EP | disclosed |