Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GALR3 | O60755 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4105383 | 0.81 | ALDH1A1 (0.52) | ALDH1A1MAPTKMT2AMEN1RXFP1 | |
| SCHEMBL3227136 | 0.79 | MAPT (0.72) | ALDH1A1MAPTKMT2AMEN1RXFP1 | |
| SCHEMBL10744154 | 0.79 | MMP2 (0.50) | ALDH1A1MAPTKMT2AMEN1RXFP1 | |
| SCHEMBL9672637 | 0.77 | ALDH1A1 (0.47) | ALDH1A1MAPTKMT2AMEN1RXFP1 | |
| SCHEMBL10808916 | 0.76 | ALDH1A1 (0.46) | ALDH1A1MAPTKMT2AMEN1RXFP1 | |
| SCHEMBL11021626 | 0.75 | ALDH1A1 (0.42) | ALDH1A1MAPTKMT2AMEN1RXFP1 | |
| SCHEMBL9673214 | 0.75 | ALDH1A1 (0.55) | ALDH1A1MAPTKMT2AMEN1RXFP1 | |
| SCHEMBL10748287 | 0.75 | MMP12 (0.48) | ALDH1A1MAPTKMT2AMEN1RXFP1 | |
| SCHEMBL10748109 | 0.74 | MAPT (0.54) | ALDH1A1MAPTKMT2AMEN1RXFP1 | |
| SCHEMBL10746820 | 0.74 | KDM4E (0.53) | ALDH1A1MAPTKMT2AMEN1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4657919-A | CARDIOVASCULAR DISORDERS | E. I. DU PONT DE NEMOURS & CO. (US) | 1987-04-14 | — | — | US | disclosed |
| US-4555517-A | Pyridone esters as inotropic agents | AMERICAN HOSPITAL SUPPLY CORPORATION (US) | 1985-11-26 | — | — | US | disclosed |