SCHEMBL9673157

SCHEMBL9673157

NC(=O)c1cc(O)c(O)cc1N

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.44
ALDH1A1 P00352 5/20 0.44
MAPT P10636 4/20 0.44
HPGD P15428 3/20 0.44
HSD17B10 Q99714 3/20 0.44
TSHR P16473 2/20 0.44
IKBKB O14920 3/20 0.44
PPM1B O75688 1/20 0.41
LCK P06239 1/20 0.39
TDP1 Q9NUW8 3/20 0.38
POLB P06746 1/20 0.38
CHUK O15111 1/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
MAPK1 P28482 1/20 0.37
CYP3A4 P08684 2/20 0.35
ALOX15 P16050 2/20 0.35
RECQL P46063 2/20 0.35
TNF P01375 1/20 0.35
HSPD1 P10809 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6209540 0.88 MAPT (0.43) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL11666352 0.88 MAPT (0.43) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL5847055 0.84 IKBKB (0.50) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL17774896 0.82 DGAT1 (0.41) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL2193090 0.80 PPM1B (0.55) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL11052232 0.79 ALDH1A1 (0.48) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL23511720 0.78 ALDH1A1 (0.52) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL10041870 0.78 ALOX15 (0.47) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL4420135 0.76 KDM4E (0.56) KDM4EALDH1A1MAPTHPGDHSD17B10
Water SCHEMBL28292285 0.76 ALDH1A1 (0.50) KDM4EALDH1A1MAPTHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120058675-A Preparation and purification method and application of quinoline derivative with biological activity 河南科技大学 2025-05-30 CN claimed
CN-120058675-A Preparation and purification method and application of quinoline derivative with biological activity 河南科技大学 2025-05-30 CN disclosed
EP-0251143-B1 2-Oxo-1-[[(Substituted Sulfonyl)Amino]-Carbonyl]Azetidines Bristol-Myers Squibb GmbH (DE) 1992-08-26 EP disclosed
US-4801705-A 2-oxo-1-(((substituted sulfonyl)amino)-carbonyl)azetidines E. R. SQUIBB & SONS, INC. (US) 1989-01-31 US disclosed
EP-0251143-A1 2-Oxo-1-[[(Substituted Sulfonyl)Amino]-Carbonyl]Azetidines Bristol-Myers Squibb GmbH (DE) 1988-01-07 EP disclosed