Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | TP53 | P04637 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | VDR | P11473 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 6/20 | 0.41 |
| ▸ | MAOA | P21397 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20777209 | 0.81 | SMN1; SMN2 (0.81) | SMN1; SMN2TP53MAPTTDP1MEN1 | |
| SCHEMBL9674712 | 0.79 | VDR (0.58) | SMN1; SMN2TP53MAPTTDP1VDR | |
| SCHEMBL3616241 | 0.79 | KDM4E (0.65) | SMN1; SMN2TP53MAPTTDP1VDR | |
| SCHEMBL2084701 | 0.76 | VDR (0.72) | SMN1; SMN2TP53MAPTTDP1VDR | |
| SCHEMBL9866483 | 0.76 | ALDH1A1 (0.67) | SMN1; SMN2TP53MAPTTDP1VDR | |
| Hydrochloric Acid SCHEMBL4727347 | 0.76 | VDR (0.56) | SMN1; SMN2TP53MAPTTDP1VDR | |
| SCHEMBL2082562 | 0.76 | LMNA (0.57) | SMN1; SMN2TP53MAPTVDRMEN1 | |
| SCHEMBL20421688 | 0.76 | TNF (0.58) | SMN1; SMN2TP53MAPTTDP1MEN1 | |
| SCHEMBL4921054 | 0.75 | KDM4E (0.57) | SMN1; SMN2TP53MAPTTDP1VDR | |
| SCHEMBL9673595 | 0.75 | VDR (0.55) | SMN1; SMN2TP53MAPTTDP1VDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0276942-B1 | 6-BETA(SUBSTITUTED)-(S)-HYDROXYMETHYLPENICILLANIC ACIDS AND DERIVATIVES THEREOF | PFIZER INC. (US) | 1992-04-01 | — | — | EP | disclosed |
| US-4782050-A | BACTERICIDES | PFIZER INC. (US) | 1988-11-01 | — | — | US | disclosed |
| EP-0276942-A1 | 6-Beta(substituted)-(S)-hydroxymethylpenicillanic acids and derivatives thereof | PFIZER INC. (US) | 1988-08-03 | — | — | EP | disclosed |