Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11636564 | 0.82 | FAAH (0.39) | FAAHRELAMEN1ALDH1A1LMNA | |
| SCHEMBL4898324 | 0.82 | RELA (0.40) | FAAHRELA | |
| SCHEMBL3220018 | 0.81 | PTPN1 (0.43) | FAAHPTPN1 | |
| SCHEMBL8091952 | 0.78 | FAAH (0.43) | FAAHPTPN1 | |
| SCHEMBL13113281 | 0.77 | FAAH (0.41) | FAAHPTPN1 | |
| Carbamic Acid SCHEMBL10399044 | 0.76 | PTPN1 (0.40) | FAAHPTPN1RELA | |
| SCHEMBL11194152 | 0.75 | HPGD (0.34) | FAAHKDM4EHPGDALDH1A1LMNA | |
| SCHEMBL4602875 | 0.75 | FAAH (0.40) | FAAHPTPN1 | |
| SCHEMBL1347954 | 0.75 | RELA (0.41) | FAAHRELA | |
| SCHEMBL13671233 | 0.75 | FAAH (0.45) | FAAHPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268295-B1 | N-ARYLSULFONYL-N'-PYRIMIDYL-(TRIAZINYL)UREA | BASF Aktiengesellschaft (DE) | 1992-10-07 | — | — | EP | claimed |
| EP-0268295-A2 | N-Arylsulfonyl-N'-pyrimidyl-(triazinyl)urea | BASF Aktiengesellschaft (DE) | 1988-05-25 | — | — | EP | claimed |
| EP-0268295-B1 | N-ARYLSULFONYL-N'-PYRIMIDYL-(TRIAZINYL)UREA | BASF Aktiengesellschaft (DE) | 1992-10-07 | — | — | EP | disclosed |
| US-5068424-A | Carbonylation of N-haloarylsulfonamide to form arylsulfonyl isocyaanate in the presence of a catalyst | NITROKEMIA IPARTELEPEK (HU) | 1991-11-26 | — | — | US | disclosed |
| US-4808211-A | HERBICIDES, PLANT GROWTH REGULATORS | BASF AKTIENGESELLSCHAFT (DE) | 1989-02-28 | — | — | US | disclosed |
| EP-0268295-A2 | N-Arylsulfonyl-N'-pyrimidyl-(triazinyl)urea | BASF Aktiengesellschaft (DE) | 1988-05-25 | — | — | EP | disclosed |