Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.46 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.46 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.46 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9678519 | 0.80 | POLB (0.40) | CA1CA2ALDH1A1 | |
| SCHEMBL9676946 | 0.80 | FLT1 (0.47) | CA1CA2PKMSLC40A1L3MBTL1 | |
| SCHEMBL9676913 | 0.79 | THRB (0.48) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL9678632 | 0.79 | SMN1; SMN2 (0.48) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL9679238 | 0.77 | MEN1 (0.46) | ALKBH2ALKBH3FTOMEN1KMT2A | |
| SCHEMBL9677246 | 0.77 | ITGB1 (0.48) | PKMTDP1MEN1KMT2ASLC40A1 | |
| SCHEMBL9678815 | 0.76 | SLC40A1 (0.47) | CA1CA2TDP1MEN1KMT2A | |
| SCHEMBL9675993 | 0.76 | THRB (0.47) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL9679243 | 0.74 | HTR6 (0.42) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL9678583 | 0.74 | SLC22A12 (0.40) | KMT2AALDH1A1NPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269141-B1 | 1-CARBAMOYL-2-PYRAZOLINE DERIVATIVES HAVING HERBICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1992-09-16 | — | — | EP | disclosed |
| US-4927452-A | 1-carbonyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1990-05-22 | — | — | US | disclosed |
| EP-0269141-A2 | 1-Carbamoyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1988-06-01 | — | — | EP | disclosed |