Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 3/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9678519 | 0.78 | POLB (0.40) | HTR6ALDH1A1MAPTITGB1ITGA4 | |
| SCHEMBL9676946 | 0.78 | FLT1 (0.47) | HTR6ALDH1A1P2RY12HSD17B10TSHR | |
| SCHEMBL9677246 | 0.78 | ITGB1 (0.48) | ALDH1A1MAPTITGB1ITGA4TSHR | |
| SCHEMBL9678815 | 0.77 | SLC40A1 (0.47) | ALDH1A1MAPT | |
| SCHEMBL9676381 | 0.77 | HTR6 (0.33) | HTR6ITGB1ITGA4 | |
| SCHEMBL9677853 | 0.75 | RIPK1 (0.49) | HTR6ALDH1A1MAPT | |
| SCHEMBL9679238 | 0.75 | MEN1 (0.46) | ALDH1A1 | |
| SCHEMBL9675932 | 0.74 | CA1 (0.50) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL9677216 | 0.73 | SLC40A1 (0.46) | ITGB1ITGA4 | |
| SCHEMBL9678583 | 0.73 | SLC22A12 (0.40) | HTR6ALDH1A1MAPTITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269141-B1 | 1-CARBAMOYL-2-PYRAZOLINE DERIVATIVES HAVING HERBICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1992-09-16 | — | — | EP | disclosed |
| US-4927452-A | 1-carbonyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1990-05-22 | — | — | US | disclosed |
| EP-0269141-A2 | 1-Carbamoyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1988-06-01 | — | — | EP | disclosed |