Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 1/20 | 0.48 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | CCR3 | P51677 | 1/20 | 0.46 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.44 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.43 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9677216 | 0.85 | SLC40A1 (0.46) | ITGB1ITGA4SLC40A1BRD4 | |
| SCHEMBL9678583 | 0.85 | SLC22A12 (0.40) | ITGB1ITGA4HRH1CCR3TRIM24 | |
| SCHEMBL9678815 | 0.84 | SLC40A1 (0.47) | SLC40A1ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL9678519 | 0.81 | POLB (0.40) | ITGB1ITGA4ALDH1A1MAPTPOLB | |
| SCHEMBL9676946 | 0.81 | FLT1 (0.47) | HRH1CCR3SLC40A1PKMALDH1A1 | |
| SCHEMBL9679238 | 0.78 | MEN1 (0.46) | SLC40A1KAT6AALDH1A1CYP3A4MEN1 | |
| SCHEMBL9679243 | 0.78 | HTR6 (0.42) | ITGB1ITGA4ALDH1A1HTTMAPT | |
| SCHEMBL9675932 | 0.77 | CA1 (0.50) | SLC40A1PKMALDH1A1MEN1HPGD | |
| SCHEMBL9678713 | 0.76 | HRH1 (0.41) | HRH1CCR3TRIM24SLC40A1KAT6A | |
| SCHEMBL9676073 | 0.74 | L3MBTL1 (0.53) | ALDH1A1MEN1KMT2AL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269141-B1 | 1-CARBAMOYL-2-PYRAZOLINE DERIVATIVES HAVING HERBICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1992-09-16 | — | — | EP | disclosed |
| US-4927452-A | 1-carbonyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1990-05-22 | — | — | US | disclosed |
| EP-0269141-A2 | 1-Carbamoyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1988-06-01 | — | — | EP | disclosed |