Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 3/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9678598 | 0.83 | P2RY12 (0.48) | HTR6P2RY12GAA | |
| SCHEMBL9678476 | 0.79 | KAT6A (0.40) | HTR6ALDH1A1PKM | |
| SCHEMBL9678253 | 0.77 | HTR6 (0.47) | HTR6PIK3C3EPHX2P2RY12GAA | |
| SCHEMBL9678675 | 0.76 | P2RY12 (0.44) | HTR6EPHX2P2RY12ALDH1A1GAA | |
| SCHEMBL9677307 | 0.75 | HTR6 (0.43) | HTR6EPHX2ALDH1A1PKM | |
| SCHEMBL9677118 | 0.75 | HTR6 (0.40) | HTR6P2RY12CNR2 | |
| SCHEMBL9676824 | 0.74 | HTR6 (0.40) | HTR6EPHX2P2RY12BRD4ALDH1A1 | |
| SCHEMBL9678605 | 0.74 | KMT2A (0.46) | EPHX2ALDH1A1 | |
| SCHEMBL9678257 | 0.73 | HTR6 (0.50) | HTR6P2RY12GAA | |
| SCHEMBL9676435 | 0.71 | CA1 (0.46) | BRD4ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269141-B1 | 1-CARBAMOYL-2-PYRAZOLINE DERIVATIVES HAVING HERBICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1992-09-16 | — | — | EP | disclosed |
| US-4927452-A | 1-carbonyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1990-05-22 | — | — | US | disclosed |
| EP-0269141-A2 | 1-Carbamoyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1988-06-01 | — | — | EP | disclosed |