Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8414903 | 0.89 | TSHR (0.45) | PTPN1RXFP1ALOX15ADORA2ACA2 | |
| SCHEMBL9335770 | 0.82 | ALDH1A1 (0.46) | GAAKDM4EALDH1A1HPGDALOX5 | |
| SCHEMBL8564405 | 0.76 | CUL4A (0.44) | CA2GAAMAPTNPSR1GPR55 | |
| SCHEMBL8559572 | 0.76 | CUL4A (0.41) | ALOX15CA2MAPTTSHRCUL4A | |
| SCHEMBL9018597 | 0.75 | KMT2A (0.41) | PTPN1ALOX15MAPTTSHRKDM4E | |
| SCHEMBL8560927 | 0.75 | ALOX5 (0.41) | CA2GAAMAPTNPSR1GPR55 | |
| SCHEMBL9018628 | 0.74 | CASP1 (0.41) | PTPN1ALOX15MAPTKDM4EALDH1A1 | |
| SCHEMBL4089116 | 0.74 | SMN1; SMN2 (0.52) | ALOX15GAAMAPTTSHRNPSR1 | |
| SCHEMBL9231055 | 0.73 | ALOX5 (0.39) | CA2CUL4AKDM4EALDH1A1ALOX5 | |
| SCHEMBL24453339 | 0.72 | PPARG (0.48) | ALOX15GAATSHRCUL4AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233150-B1 | PROCESS FOR THE PREPARATION OF 2-(IMIDAZOLIN-2-YL)-PYRIDINE AND LIKE QUINOLINE-3-CARBOXYLIC ACIDS | CIBA-GEIGY AG (CH) | 1992-11-11 | — | — | EP | disclosed |