Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | IDE | P14735 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018597 | 0.89 | KMT2A (0.41) | CASP1HSD17B10KMT2AIDEDHODH | |
| SCHEMBL9677441 | 0.74 | PTPN1 (0.41) | KMT2AMAPTKDM4EALDH1A1PTPN1 | |
| SCHEMBL6499213 | 0.72 | HSD17B10 (0.44) | CASP1HSD17B10KMT2AIDEMAPT | |
| SCHEMBL27465614 | 0.72 | KMO (0.56) | KMT2ADHODHPOLBMAPTALDH1A1 | |
| SCHEMBL164778 | 0.70 | KMT2A (0.50) | KMT2APOLBMAPTKDM4EALOX15 | |
| SCHEMBL31167429 | 0.70 | ALDH1A1 (0.48) | KMT2AMAPTKDM4EALDH1A1ALOX15 | |
| SCHEMBL3328767 | 0.70 | ALDH1A1 (0.48) | KMT2AMAPTKDM4EALDH1A1ALOX15 | |
| SCHEMBL1178859 | 0.69 | MEN1 (0.55) | KMT2AIDEPOLBMAPTKDM4E | |
| SCHEMBL9573804 | 0.69 | ALOX15 (0.52) | ALOX15 | |
| SCHEMBL8414903 | 0.69 | TSHR (0.45) | HSD17B10KMT2AMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0720988-A1 | Pseudopeptides containing trifluoromethyl substituted 2-azabicyclooctane | BAYER AG (DE) | 1996-07-10 | — | — | EP | disclosed |