Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 3/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846101 | 0.85 | ALDH1A1 (0.38) | MEN1ALDH1A1HPGDKMT2AHCAR2 | |
| SCHEMBL9601892 | 0.83 | ALDH1A1 (0.36) | MEN1ALDH1A1HPGDKMT2AHCAR2 | |
| SCHEMBL9449230 | 0.76 | MAPT (0.50) | MEN1KMT2AHCAR2NPC1RAB9A | |
| SCHEMBL6366768 | 0.76 | ALDH1A1 (0.35) | MEN1ALDH1A1HPGDKMT2AGLA | |
| SCHEMBL9280614 | 0.72 | PIK3CD (0.42) | MEN1ALDH1A1HPGDKMT2AGLA | |
| SCHEMBL9680858 | 0.72 | ALDH1A1 (0.32) | MEN1ALDH1A1HPGDKMT2AHCAR2 | |
| SCHEMBL9846133 | 0.70 | PIK3CD (0.42) | MEN1ALDH1A1HPGDKMT2AHCAR2 | |
| SCHEMBL9283877 | 0.69 | ALDH1A1 (0.39) | MEN1ALDH1A1HPGDKMT2AGLA | |
| SCHEMBL9280809 | 0.68 | ALDH1A1 (0.38) | MEN1ALDH1A1HPGDKMT2AGLA | |
| SCHEMBL9846239 | 0.67 | MEN1 (0.32) | MEN1ALDH1A1HPGDKMT2AHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481802-A1 | Hydroxylated inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1992-04-22 | — | — | EP | claimed |
| EP-0481802-A1 | Hydroxylated inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1992-04-22 | — | — | EP | disclosed |