Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9766551 | 0.86 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2MAPK1LMNASLC6A4 | |
| SCHEMBL10384878 | 0.83 | POLB (0.42) | ALDH1A1SMN1; SMN2LMNASLC6A4KDM4E | |
| SCHEMBL10384419 | 0.83 | CA1 (0.47) | TAS1R3TAS1R1ALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL10384260 | 0.83 | CES1 (0.41) | TSHRSMN1; SMN2LMNAKMT2A | |
| SCHEMBL9766565 | 0.81 | ALDH1A1 (0.49) | ALDH1A1TSHRSMN1; SMN2MAPK1LMNA | |
| SCHEMBL9679848 | 0.81 | PPARA (0.42) | ALDH1A1LMNAMAPTGAA | |
| SCHEMBL10885981 | 0.80 | ALDH1A1 (0.39) | TAS1R3TAS1R1ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL9681309 | 0.79 | MLYCD (0.40) | ALDH1A1KDM4EMEN1KMT2AMLYCD | |
| SCHEMBL9766582 | 0.79 | MLYCD (0.32) | ALDH1A1MLYCD | |
| SCHEMBL9680487 | 0.75 | MAPT (0.46) | ALDH1A1SMN1; SMN2MAPK1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992547-A | Aminoaryl ketone photoinitiators | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |
| US-4960746-A | A-HYDROXY-OR A-AMINO-ACETOPHENONES AND A TITANOCENE COMPOUND SUBSTITUTED BY FLUORINE | CIBA-GEIGY CORPORATION (US) | 1990-10-02 | — | — | US | disclosed |
| US-4582862-A | QUICK-SETTING PRINTING INKS BASED ON ACRYLATED RESINS | CIBA-GEIGY CORPORATION (US) | 1986-04-15 | — | — | US | disclosed |