Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | HPGD | P15428 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9681309 | 0.87 | MLYCD (0.40) | ALDH1A1HPGDRAB9AHTTHDAC1 | |
| SCHEMBL10384419 | 0.83 | CA1 (0.47) | ALDH1A1RAB9AHTTMAPTHSD17B10 | |
| SCHEMBL10384878 | 0.83 | POLB (0.42) | ALDH1A1HPGDRAB9AHTTMAPT | |
| SCHEMBL10384260 | 0.83 | CES1 (0.41) | HPGDTSHRSMN1; SMN2LMNAPOLB | |
| SCHEMBL9679848 | 0.81 | PPARA (0.42) | ALDH1A1HPGDRAB9AMAPTGAA | |
| SCHEMBL9766563 | 0.81 | TAS1R3 (0.42) | ALDH1A1HTTMAPTTSHRKDM4E | |
| SCHEMBL9766582 | 0.79 | MLYCD (0.32) | ALDH1A1MLYCD | |
| SCHEMBL9766551 | 0.78 | ALDH1A1 (0.43) | ALDH1A1HPGDRAB9AHTTMAPT | |
| SCHEMBL9680487 | 0.75 | MAPT (0.46) | ALDH1A1HPGDRAB9AHTTMAPT | |
| SCHEMBL9681018 | 0.74 | ALDH1A1 (0.50) | ALDH1A1HPGDRAB9AHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992547-A | Aminoaryl ketone photoinitiators | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |
| US-4960746-A | A-HYDROXY-OR A-AMINO-ACETOPHENONES AND A TITANOCENE COMPOUND SUBSTITUTED BY FLUORINE | CIBA-GEIGY CORPORATION (US) | 1990-10-02 | — | — | US | disclosed |