Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9681063 | 0.84 | KDM4E (0.51) | KMT2AALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL28132328 | 0.82 | POLB (0.55) | KMT2AALDH1A1MAPTMEN1TDP1 | |
| SCHEMBL11277290 | 0.80 | POLB (0.53) | KMT2AALDH1A1GAAMAPTMEN1 | |
| SCHEMBL9681829 | 0.80 | TP53 (0.54) | ALDH1A1GAASMN1; SMN2MAPTTDP1 | |
| SCHEMBL11776210 | 0.78 | KMT2A (0.64) | KMT2AALDH1A1MAPTMEN1TDP1 | |
| SCHEMBL4816596 | 0.78 | KMT2A (0.59) | KMT2ACYP1A2CYP2C19TSHRALDH1A1 | |
| SCHEMBL11204741 | 0.77 | MAPT (0.49) | KMT2ACYP1A2CYP2C19TSHRALDH1A1 | |
| SCHEMBL9681845 | 0.77 | MAPT (0.49) | KMT2ATSHRALDH1A1MAPTMEN1 | |
| SCHEMBL9680731 | 0.76 | ALDH1A1 (0.44) | KMT2ATSHRALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL9681098 | 0.76 | KMT2A (0.49) | KMT2ACYP1A2TSHRALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153335-A | Reacting halophthalic anhydride and alkali metal salt with acid or acid derivative catalyst | OCCIDENTAL CHEMICAL CORPORATION (US) | 1992-10-06 | — | — | US | claimed |
| EP-0460687-A2 | Process for the preparation of oxydiphthalic anhydride and acyloxyphthalic anhydrides | OCCIDENTAL CHEMICAL CORPORATION (US) | 1991-12-11 | — | — | EP | claimed |