Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | PYGL | P06737 | 11/20 | 0.53 |
| ▸ | PYGM | P11217 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9681882 | 0.86 | KMT2A (0.57) | TP53MAPTGAATDP1ALOX5 | |
| SCHEMBL9448725 | 0.81 | ALOX5 (0.65) | TP53MAPTGAATDP1ALOX5 | |
| SCHEMBL8566918 | 0.80 | ALOX5 (0.77) | TP53MAPTGAATDP1ALOX5 | |
| SCHEMBL9681063 | 0.80 | KDM4E (0.51) | PYGLPYGMMAPTGAATDP1 | |
| SCHEMBL9680701 | 0.80 | KMT2A (0.48) | MAPTGAATDP1ALDH1A1NPC1 | |
| SCHEMBL28469904 | 0.79 | CES2 (0.52) | TP53PYGLPYGMMAPTGAA | |
| SCHEMBL28132328 | 0.78 | POLB (0.55) | PYGLPYGMMAPTTDP1ALDH1A1 | |
| SCHEMBL9324004 | 0.78 | ALDH1A1 (0.60) | TP53MAPTGAATDP1ALDH1A1 | |
| SCHEMBL4721013 | 0.78 | CES2 (0.70) | TP53MAPTALOX5ALDH1A1KDM4E | |
| SCHEMBL1546357 | 0.77 | ALOX5 (0.68) | TP53MAPTTDP1ALOX5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153335-A | Reacting halophthalic anhydride and alkali metal salt with acid or acid derivative catalyst | OCCIDENTAL CHEMICAL CORPORATION (US) | 1992-10-06 | — | — | US | claimed |
| EP-0460687-A2 | Process for the preparation of oxydiphthalic anhydride and acyloxyphthalic anhydrides | OCCIDENTAL CHEMICAL CORPORATION (US) | 1991-12-11 | — | — | EP | claimed |