Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9601892 | 0.89 | ALDH1A1 (0.36) | ALDH1A1MEN1HPGDKMT2AGLA | |
| SCHEMBL9284917 | 0.87 | ALDH1A1 (0.35) | ALDH1A1MEN1HPGDKMT2AGLA | |
| SCHEMBL9280809 | 0.76 | ALDH1A1 (0.38) | ALDH1A1MEN1HPGDKMT2AGLA | |
| SCHEMBL9455992 | 0.76 | HCAR2 (0.33) | ALDH1A1MEN1HPGDKMT2AHCAR2 | |
| SCHEMBL9283236 | 0.72 | ALDH1A1 (0.41) | ALDH1A1MEN1HPGDKMT2AGLA | |
| SCHEMBL9682811 | 0.72 | HCAR2 (0.37) | ALDH1A1MEN1HPGDKMT2AGLA | |
| SCHEMBL9680867 | 0.72 | MEN1 (0.36) | ALDH1A1MEN1HPGDKMT2AGLA | |
| SCHEMBL9846244 | 0.71 | APOBEC3A (0.30) | — | |
| SCHEMBL9455991 | 0.70 | HCAR2 (0.34) | HCAR2 | |
| SCHEMBL9846309 | 0.70 | FABP4 (0.31) | ALDH1A1MEN1HPGDKMT2AGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481802-A1 | Hydroxylated inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1992-04-22 | — | — | EP | claimed |
| EP-0481802-A1 | Hydroxylated inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1992-04-22 | — | — | EP | disclosed |