Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9681478 | 0.89 | ALOX5 (0.40) | ABCC9L3MBTL1KCNA5 | |
| SCHEMBL9193747 | 0.84 | TYK2 (0.36) | ABCC9 | |
| SCHEMBL9680848 | 0.80 | KCNE1 (0.46) | ABCC9L3MBTL1KDM4E | |
| SCHEMBL9680855 | 0.79 | KCNE1 (0.47) | ABCC9TP53 | |
| SCHEMBL9192059 | 0.78 | KCNE1 (0.43) | ALDH1A1ABCC9L3MBTL1 | |
| SCHEMBL9194983 | 0.77 | MAPT (0.44) | ALDH1A1MAPTRECQLABCC9KCNA5 | |
| SCHEMBL9200569 | 0.76 | CA12 (0.43) | ALDH1A1MAPTRECQLALOX15ABCC9 | |
| SCHEMBL9200576 | 0.76 | CA12 (0.43) | ALDH1A1MAPTRECQLALOX15ABCC9 | |
| SCHEMBL9200557 | 0.76 | CA12 (0.43) | ALDH1A1MAPTRECQLALOX15ABCC9 | |
| SCHEMBL9193528 | 0.76 | ABCB1 (0.52) | ABCC9MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112839-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-05-12 | — | — | US | disclosed |
| EP-0406656-A1 | Chroman derivatives | MERCK PATENT GmbH (DE) | 1991-01-09 | — | — | EP | disclosed |