Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9680959 | 0.89 | ALDH1A1 (0.41) | L3MBTL1ABCC9KCNA5 | |
| SCHEMBL9193747 | 0.87 | TYK2 (0.36) | PDPK1ABCC9 | |
| SCHEMBL9680848 | 0.82 | KCNE1 (0.46) | L3MBTL1ABCC9 | |
| SCHEMBL9682025 | 0.81 | LMNA (0.34) | L3MBTL1ABCC9KCNA5 | |
| SCHEMBL9680855 | 0.81 | KCNE1 (0.47) | ABCC9 | |
| SCHEMBL9192059 | 0.80 | KCNE1 (0.43) | L3MBTL1ABCC9 | |
| SCHEMBL9197134 | 0.80 | ABCC9 (0.38) | ALOX5ABCC9KCNA5 | |
| SCHEMBL9192434 | 0.78 | KCNA5 (0.39) | ALOX5ABCC9KCNA5 | |
| SCHEMBL9680937 | 0.78 | ABCC9 (0.40) | L3MBTL1ABCC9 | |
| SCHEMBL9193528 | 0.78 | ABCB1 (0.52) | ABCC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112839-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-05-12 | — | — | US | disclosed |
| EP-0406656-A1 | Chroman derivatives | MERCK PATENT GmbH (DE) | 1991-01-09 | — | — | EP | disclosed |