Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9680485 | 0.78 | ALDH1A1 (0.53) | RAB9ANPC1HPGDALDH1A1MAPT | |
| SCHEMBL9314765 | 0.74 | HPGD (0.56) | RAB9ANPC1HPGDKCNK3ALDH1A1 | |
| SCHEMBL855138 | 0.74 | ALDH1A1 (0.61) | RAB9ANPC1HPGDALDH1A1MAPT | |
| SCHEMBL3638309 | 0.73 | KCNK3 (0.82) | RAB9ANPC1HPGDKCNK3ALDH1A1 | |
| SCHEMBL12260649 | 0.72 | RAB9A (0.58) | RAB9ANPC1HPGDKCNK3ALDH1A1 | |
| SCHEMBL11254993 | 0.72 | HTT (0.44) | RAB9AMAPTKMT2AMEN1KDM4E | |
| SCHEMBL5949981 | 0.72 | MAPT (0.59) | RAB9ANPC1HPGDALDH1A1MAPT | |
| SCHEMBL194873 | 0.72 | ALDH1A1 (0.59) | RAB9ANPC1HPGDALDH1A1MAPT | |
| SCHEMBL11350456 | 0.72 | NAPRT (0.52) | RAB9ANPC1HPGDALDH1A1MAPT | |
| SCHEMBL1646972 | 0.72 | NAPRT (0.46) | RAB9ANPC1HPGDMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145885-A | Morpholine compound, binders | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | disclosed |
| US-4992547-A | Aminoaryl ketone photoinitiators | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |