Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL855138 | 0.80 | ALDH1A1 (0.61) | ALDH1A1MAPTHPGDHDAC1HDAC6 | |
| SCHEMBL194873 | 0.79 | ALDH1A1 (0.59) | ALDH1A1MAPTHPGDHDAC1HDAC6 | |
| SCHEMBL5949981 | 0.79 | MAPT (0.59) | ALDH1A1MAPTHPGDHDAC1HDAC6 | |
| SCHEMBL9681004 | 0.78 | RAB9A (0.53) | ALDH1A1MAPTHPGDHDAC1HDAC6 | |
| SCHEMBL9681277 | 0.77 | GAA (0.46) | ALDH1A1MAPTHPGDHDAC1HDAC6 | |
| SCHEMBL9681080 | 0.77 | ALDH1A1 (0.57) | ALDH1A1MAPTHPGDHDAC1HDAC6 | |
| SCHEMBL727322 | 0.77 | ALDH1A1 (0.57) | ALDH1A1MAPTHPGDHDAC1HDAC6 | |
| SCHEMBL9681711 | 0.77 | MLYCD (0.42) | ALDH1A1HPGDHDAC1HDAC6NPC1 | |
| SCHEMBL14506290 | 0.76 | ALDH1A1 (0.52) | ALDH1A1MAPTHPGDHDAC1HDAC6 | |
| SCHEMBL10384826 | 0.76 | CES1 (0.56) | ALDH1A1MAPTHPGDHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145885-A | Morpholine compound, binders | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | disclosed |
| US-4992547-A | Aminoaryl ketone photoinitiators | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |