Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9681734 | 0.84 | CYP3A4 (0.54) | KMT2AALDH1A1MAPTLMNAKDM4E | |
| SCHEMBL10456871 | 0.82 | CYP3A4 (0.55) | KMT2AALDH1A1MAPTLMNAKDM4E | |
| SCHEMBL10458478 | 0.80 | FKBP1A (0.51) | KMT2AALDH1A1MAPTLMNAKDM4E | |
| SCHEMBL10458636 | 0.79 | THRB (0.44) | KMT2AALDH1A1MAPTLMNAKDM4E | |
| SCHEMBL12855171 | 0.79 | THRB (0.44) | KMT2AALDH1A1LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL10458820 | 0.79 | HRH3 (0.46) | KMT2AALDH1A1MAPTLMNAKDM4E | |
| SCHEMBL12013268 | 0.78 | LMNA (0.43) | ALDH1A1MAPTLMNAKDM4ECYP3A4 | |
| SCHEMBL9680457 | 0.78 | GSK3B (0.49) | ALDH1A1MAPTLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL10458802 | 0.78 | ATM (0.43) | KMT2AALDH1A1MAPTLMNAKDM4E | |
| SCHEMBL18883176 | 0.78 | CYP3A4 (0.48) | KMT2AALDH1A1MAPTLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145885-A | Morpholine compound, binders | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | disclosed |
| US-4992547-A | Aminoaryl ketone photoinitiators | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |