Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PHGDH | O43175 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10458636 | 0.98 | THRB (0.44) | ATMTHRBLMNAGAAPRKDC | |
| SCHEMBL9680457 | 0.85 | GSK3B (0.49) | ATMTHRBLMNAGAAPRKDC | |
| SCHEMBL12013268 | 0.85 | LMNA (0.43) | THRBLMNAHPGDMAPTALDH1A1 | |
| SCHEMBL10456871 | 0.84 | CYP3A4 (0.55) | LMNAHPGDMAPTALDH1A1KDM4E | |
| SCHEMBL9679919 | 0.83 | MAPT (0.48) | THRBLMNAGAAHPGDMAPT | |
| SCHEMBL9681734 | 0.83 | CYP3A4 (0.54) | LMNAHPGDMAPTALDH1A1KDM4E | |
| SCHEMBL12855171 | 0.83 | THRB (0.44) | THRBLMNAHPGDALDH1A1KDM4E | |
| SCHEMBL274970 | 0.82 | SMN1; SMN2 (0.51) | THRBLMNAHPGDMAPTALDH1A1 | |
| SCHEMBL306036 | 0.82 | THRB (0.44) | THRBLMNAHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL9679446 | 0.82 | MAPT (0.47) | THRBLMNAGAAHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4900823-A | PHOTOINITIATORS FOR PHOTOCURING | CIBA-GEIGY CORPORATION (US) | 1990-02-13 | — | — | US | disclosed |
| US-4739052-A | PHOTOINITIATORS | CIBA-GEIGY CORPORATION (US) | 1988-04-19 | — | — | US | disclosed |
| US-4559371-A | FOR PRINTING INKS AND PAINTS | CIBA GEIGY CORPORATION (US) | 1985-12-17 | — | — | US | disclosed |