Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT2 | O75908 | 2/20 | 0.53 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.43 |
| ▸ | ITGAV | P06756 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9679311 | 0.86 | SOAT2 (0.59) | SOAT2SOAT1KMT2ALMNA | |
| SCHEMBL9679315 | 0.86 | SOAT2 (0.59) | SOAT2SOAT1KMT2ALMNA | |
| SCHEMBL9680183 | 0.86 | ANPEP (0.63) | SOAT2SOAT1ANPEP | |
| SCHEMBL9679677 | 0.85 | SOAT2 (0.57) | SOAT2SOAT1KMT2ALMNA | |
| SCHEMBL9680770 | 0.83 | LMNA (0.62) | SOAT2SOAT1KMT2ALMNACTSL | |
| SCHEMBL9679632 | 0.81 | USP30 (0.48) | ANPEPCTSLITGB3ITGB1ITGAV | |
| Benzene SCHEMBL9851044 | 0.81 | LMNA (0.50) | KMT2ALMNA | |
| SCHEMBL9679723 | 0.80 | SOAT2 (0.57) | SOAT2SOAT1KMT2ALMNA | |
| SCHEMBL9851026 | 0.80 | CTSL (0.61) | CTSL | |
| SCHEMBL8432604 | 0.79 | NAALAD2 (0.60) | ITGB3ITGB1ITGAVITGA2BITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153226-A | Administering as anticholesterol agents, for atherosclerosis | WARNER-LAMBERT COMPANY (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0415413-A1 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |