Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.52 |
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11084878 | 0.84 | GAA (0.54) | ALDH1A1SMN1; SMN2RAB9AMAPTNPC1 | |
| SCHEMBL2013741 | 0.75 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2RAB9AMAPTNPC1 | |
| SCHEMBL57063 | 0.75 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2RAB9AMAPTNPC1 | |
| SCHEMBL29175534 | 0.75 | SMN1; SMN2 (0.49) | ALDH1A1SMN1; SMN2RAB9AMAPTNPC1 | |
| SCHEMBL3700972 | 0.74 | GAA (0.72) | ALDH1A1SMN1; SMN2RAB9AMAPTNPC1 | |
| SCHEMBL52410 | 0.74 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2MAPTNPC1HPGD | |
| SCHEMBL3181932 | 0.73 | CES2 (0.58) | ALDH1A1SMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL3732383 | 0.73 | CES2 (0.58) | ALDH1A1SMN1; SMN2RAB9AMAPTNPC1 | |
| SCHEMBL28838517 | 0.72 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2RAB9AMAPTNPC1 | |
| SCHEMBL28618917 | 0.72 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2RAB9AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145885-A | Morpholine compound, binders | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | disclosed |
| US-4992547-A | Aminoaryl ketone photoinitiators | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |
| EP-0138754-A2 | Photocurable compositions | CIBA-GEIGY AG (CH) | 1985-04-24 | — | — | EP | disclosed |