Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9213879 | 0.89 | L3MBTL1 (0.39) | HTTMAPTNPSR1TP53POLB | |
| SCHEMBL9221161 | 0.89 | L3MBTL1 (0.38) | MAPTNPSR1TP53L3MBTL1SMN1; SMN2 | |
| SCHEMBL5500482 | 0.89 | MEN1 (0.44) | MAPTLMNANPSR1TP53L3MBTL1 | |
| SCHEMBL9218677 | 0.88 | L3MBTL1 (0.39) | HTTMAPTNPSR1TP53L3MBTL1 | |
| SCHEMBL9215129 | 0.88 | L3MBTL1 (0.41) | HTTMAPTNPSR1TP53L3MBTL1 | |
| SCHEMBL9215732 | 0.88 | EGFR (0.38) | HTTMAPTNPSR1TP53L3MBTL1 | |
| SCHEMBL9681518 | 0.87 | NPC1 (0.39) | MAPTTP53L3MBTL1THRBMEN1 | |
| SCHEMBL9219657 | 0.87 | L3MBTL1 (0.36) | MAPTTP53L3MBTL1THRBMEN1 | |
| SCHEMBL9219654 | 0.87 | L3MBTL1 (0.39) | MAPTNPSR1TP53L3MBTL1MEN1 | |
| SCHEMBL9220263 | 0.86 | TP53 (0.46) | MAPTLMNATP53L3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512570-A1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |