Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9216807 | 0.85 | ALDH1A1 (0.52) | RAB9ANPC1ALDH1A1LMNATP53 | |
| SCHEMBL9219766 | 0.84 | ALDH1A1 (0.53) | ALDH1A1LMNATP53MAPK1MAPT | |
| SCHEMBL9221111 | 0.84 | ALDH1A1 (0.51) | RAB9ANPC1ALDH1A1LMNATP53 | |
| SCHEMBL9681584 | 0.83 | MAPT (0.57) | RAB9ANPC1ALDH1A1LMNATP53 | |
| SCHEMBL9683410 | 0.82 | ALDH1A1 (0.49) | ALDH1A1LMNAMAPK1MAPTHPGD | |
| SCHEMBL9681469 | 0.82 | RAB9A (0.55) | RAB9ANPC1ALDH1A1LMNAMAPT | |
| SCHEMBL9212938 | 0.82 | KDM4E (0.53) | RAB9ANPC1ALDH1A1LMNATP53 | |
| SCHEMBL9217619 | 0.81 | RXFP1 (0.51) | ALDH1A1TP53MAPTHPGDSMN1; SMN2 | |
| SCHEMBL9209998 | 0.81 | TP53 (0.44) | RAB9ANPC1ALDH1A1LMNATP53 | |
| SCHEMBL9212376 | 0.80 | HPGD (0.52) | ALDH1A1LMNATP53MAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512570-A1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |