Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9219295 | 0.94 | TDP1 (0.53) | KDM4ERECQLRAB9ANPC1KMT2A | |
| SCHEMBL9218548 | 0.94 | TDP1 (0.57) | KDM4ERAB9ANPC1ALDH1A1TSHR | |
| SCHEMBL9216044 | 0.90 | SAE1 (0.54) | KDM4ERAB9ANPC1ALDH1A1TSHR | |
| SCHEMBL9218014 | 0.90 | L3MBTL1 (0.58) | KDM4ERAB9ANPC1KMT2AALDH1A1 | |
| SCHEMBL9216807 | 0.85 | ALDH1A1 (0.52) | KDM4ERAB9ANPC1KMT2AALDH1A1 | |
| SCHEMBL9219766 | 0.84 | ALDH1A1 (0.53) | KDM4EALDH1A1TSHRHPGDPOLB | |
| SCHEMBL9221111 | 0.84 | ALDH1A1 (0.51) | KDM4ERAB9ANPC1KMT2AALDH1A1 | |
| SCHEMBL9212926 | 0.83 | L3MBTL1 (0.57) | KDM4ERECQLRAB9ANPC1KMT2A | |
| SCHEMBL9217935 | 0.82 | LMNA (0.42) | KDM4ERAB9ANPC1KMT2AALDH1A1 | |
| SCHEMBL9681590 | 0.82 | RAB9A (0.50) | RAB9ANPC1KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512570-B1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-10-11 | — | — | EP | disclosed |
| EP-0512570-A1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |