Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | SI | P14410 | 2/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 4/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9680472 | 0.88 | MGAM (0.41) | MGAMGAASIMGAM2FAAH | |
| SCHEMBL9318303 | 0.83 | MGAM (0.44) | MGAMGAASIMGAM2 | |
| SCHEMBL3909146 | 0.83 | MGAM (0.48) | MGAMGAASIMGAM2TDP1 | |
| SCHEMBL2381597 | 0.81 | MGAM (0.46) | MGAMGAASIMGAM2HDAC7 | |
| SCHEMBL2706936 | 0.80 | LMNA (0.42) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| SCHEMBL29190726 | 0.79 | FAAH (0.49) | MGAMGAASIMGAM2HDAC7 | |
| SCHEMBL10430878 | 0.78 | ALDH1A1 (0.48) | HDAC8TDP1CHRM1AKR1A1CHRM3 | |
| SCHEMBL446905 | 0.78 | — | — | |
| SCHEMBL14764391 | 0.78 | TSHR (0.52) | TSHRALDH1A1LMNACA2 | |
| SCHEMBL28002469 | 0.78 | MGAM (0.43) | MGAMGAASIMGAM2HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12577591-B2 | Microorganisms and methods for increasing co-factors | GENOMATICA, INC. (US) | 2026-03-17 | — | — | US | claimed |
| US-20240150798-A1 | MICROORGANISMS AND METHODS FOR PRODUCING (3R)-HYDROXYBUTYL (3R)-HYDROXYBUTYRATE | GENOMATICA INC (US) | 2024-05-09 | — | — | US | claimed |
| US-11814664-B2 | Microorganisms and methods for producing (3R)-hydroxybutyl (3R)-hydroxybutyrate | GENOMATICA, INC. (US) | 2023-11-14 | — | — | US | claimed |
| US-20230285348-A1 | COMPOSITIONS AND METHODS FOR WEIGHT LOSS MAINTENANCE | UNIVERSITY OF SOUTH FLORIDA | 2023-09-14 | — | — | US | claimed |
| US-20220403420-A1 | MICROORGANISMS AND METHODS FOR INCREASING CO-FACTORS | AGAIN BIO APS (DK) | 2022-12-22 | — | — | US | claimed |
| EP-4051657-A1 | MICROORGANISMS AND METHODS FOR REDUCING BY-PRODUCTS | Genomatica, Inc. (US) | 2022-09-07 | — | — | EP | claimed |
| EP-4048781-A1 | MICROORGANISMS AND METHODS FOR INCREASING CO-FACTORS | Genomatica, Inc. (US) | 2022-08-31 | — | — | EP | claimed |
| CN-114728871-A | Microorganisms and methods for reducing by-products | 基因组股份公司 | 2022-07-08 | — | — | CN | claimed |
| WO-2021086944-A1 | MICROORGANISMS AND METHODS FOR RECUCING BY-PRODUCTS | GENOMATICA, INC. (US) | 2021-05-06 | — | — | WO | claimed |
| WO-2021081185-A1 | MICROORGANISMS AND METHODS FOR INCREASING CO-FACTORS | GENOMATICA, INC. (US) | 2021-04-29 | — | — | WO | claimed |
| US-20200397736-A1 | COMPOSITIONS AND METHODS FOR WEIGHT LOSS MAINTENANCE | UNIVERSITY OF SOUTH FLORIDA | 2020-12-24 | — | — | US | claimed |
| EP-3723511-A1 | COMPOSITIONS AND METHODS FOR WEIGHT LOSS MAINTENANCE | University of South Florida (US) | 2020-10-21 | — | — | EP | claimed |
| WO-2019118624-A1 | COMPOSITIONS AND METHODS FOR WEIGHT LOSS MAINTENANCE | UNIVERSITY OF SOUTH FLORIDA (US) | 2019-06-20 | — | — | WO | claimed |
| CN-108042516-A | Application of R, S-1,3- the butanediol acetoacetate diester in prevention or treatment decompression medicine is prepared | 中国人民解放军第二军医大学 | 2018-05-18 | — | — | CN | claimed |
| US-20170266147-A1 | METHODS OF INCREASING LATENCY OF ANESTHETIC INDUCTION USING KETONE SUPPLEMENTATION | NAVY, SECRETARY OF THE UNITED STATES OF AMERICA | 2017-09-21 | — | — | US | claimed |
| US-20160108442-A1 | MICROORGANISMS AND METHODS FOR PRODUCING (3R)-HYDROXYBUTYL (3R)-HYDROXYBUTYRATE | GENOMATICA, INC. (US) | 2016-04-21 | — | — | US | claimed |
| US-12577591-B2 | Microorganisms and methods for increasing co-factors | GENOMATICA, INC. (US) | 2026-03-17 | — | — | US | disclosed |
| US-20240150798-A1 | MICROORGANISMS AND METHODS FOR PRODUCING (3R)-HYDROXYBUTYL (3R)-HYDROXYBUTYRATE | GENOMATICA INC (US) | 2024-05-09 | — | — | US | disclosed |
| US-4997976-A | Use of 1,3-butanediol acetoacetate in parenteral oral nutrition | BRUNENGRABER HENRI (CA) | 1991-03-05 | — | — | US | disclosed |
| EP-0318357-A2 | 1,3-Butanediol acetoacetate and its use in parenteral and oral nutrition | Brunengraber, Henri (CA) | 1989-05-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240150798-A1 | MICROORGANISMS AND METHODS FOR PRODUCING (3R)-HYDROXYBUTYL (3R)-HYDROXYBUTYRATE | ACACB, GRHPR, HSD17B10 | MGAM 208/4885GAA 613/4885SI 343/4885 |
| US-11814664-B2 | Microorganisms and methods for producing (3R)-hydroxybutyl (3R)-hydroxybutyrate | ACACB, GRHPR, HSD17B10 | MGAM 208/4885GAA 613/4885SI 343/4885 |
| US-12577591-B2 | Microorganisms and methods for increasing co-factors | ABAT, HADHB, MMAB | MGAM 407/4885GAA 878/4885SI 2509/4885 |
| US-20160108442-A1 | MICROORGANISMS AND METHODS FOR PRODUCING (3R)-HYDROXYBUTYL (3R)-HYDROXYBUTYRATE | ACACB, GRHPR, HSD17B10 | MGAM 208/4885GAA 613/4885SI 343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.