Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 4/20 | 0.38 |
| ▸ | ACHE | P22303 | 4/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22580679 | 0.83 | ESR1 (0.50) | ESR1ESR2ALDH1A1NPC1RAB9A | |
| SCHEMBL22044364 | 0.82 | ESR1 (0.55) | ESR1ESR2ALDH1A1MAPTMAPK1 | |
| SCHEMBL5028191 | 0.82 | LTA4H (0.52) | ALDH1A1NPC1RAB9AMAPTMEN1 | |
| SCHEMBL28908188 | 0.81 | ALDH1A1 (0.66) | ESR1ESR2ALDH1A1NPC1RAB9A | |
| SCHEMBL7262393 | 0.81 | ALDH1A1 (0.66) | ESR1ESR2ALDH1A1NPC1RAB9A | |
| SCHEMBL10038560 | 0.78 | LTA4H (0.57) | ESR1ESR2ALDH1A1NPC1RAB9A | |
| SCHEMBL10924561 | 0.78 | RAB9A (0.47) | ALDH1A1NPC1RAB9AMAPTHPGD | |
| SCHEMBL23530428 | 0.78 | ALDH1A1 (0.47) | ESR1ESR2ALDH1A1NPC1RAB9A | |
| SCHEMBL9303633 | 0.76 | MAOA (0.47) | ESR1ESR2ALDH1A1NPC1RAB9A | |
| SCHEMBL22051073 | 0.76 | ESR1 (0.49) | ESR1ESR2ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3167163-A | — | — | None | — | — | JP | disclosed |
| US-5112942-A | Copolymers, aromatic diamine with alkyl substituents and phenoxy substituted aromatic diamine, resistance to stess cracking | ETHYL CORPORATION (US) | 1992-05-12 | — | — | US | disclosed |
| JP-H03167163-A | AROMATIC DIAMINE | MITSUBISHI PETROCHEM CO LTD | 1991-07-19 | — | — | JP | disclosed |