Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18956930 | 0.87 | MEN1 (0.44) | LTA4HTSHRMAOAMAOBMEN1 | |
| SCHEMBL2190601 | 0.86 | ALDH1A1 (0.55) | TSHRMEN1KMT2AALDH1A1PPARG | |
| SCHEMBL11083127 | 0.84 | LTA4H (0.50) | LTA4HMAOAMEN1KMT2ANPC1 | |
| SCHEMBL10605236 | 0.83 | TEAD4 (0.61) | TSHRMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL31238589 | 0.83 | ALDH1A1 (0.69) | TSHRMAOAMAOBMEN1KMT2A | |
| SCHEMBL9681691 | 0.82 | ESR1 (0.47) | LTA4HMAOAMAOBMEN1KMT2A | |
| SCHEMBL12925863 | 0.82 | LTA4H (0.57) | LTA4HTSHRMAOAMAOBMEN1 | |
| SCHEMBL9297973 | 0.79 | MAOA (0.54) | LTA4HTSHRMAOAMAOBMEN1 | |
| SCHEMBL8517685 | 0.78 | LTA4H (0.52) | LTA4HTSHRMAOBMEN1KMT2A | |
| SCHEMBL14036886 | 0.78 | LTA4H (0.52) | LTA4HTSHRMAOAMAOBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641852-B | Sulfonamides as GPR 40-and GPR 120-agonists | 东佩制药股份公司 | 2022-08-26 | — | — | CN | disclosed |
| US-11084824-B2 | Pyrazolopyrimidine derivatives, preparation method thereof, and pharmaceutical composition for use in preventing or treating cancer, autoimmune disease and brain disease containing the same as an active ingredient | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2021-08-10 | — | — | US | disclosed |
| US-11084824-B2 | Pyrazolopyrimidine derivatives, preparation method thereof, and pharmaceutical composition for use in preventing or treating cancer, autoimmune disease and brain disease containing the same as an active ingredient | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2021-08-10 | — | — | US | disclosed |
| EP-3497085-B1 | SULFONAMIDES AS GPR40- AND GPR120-AGONISTS | DOMPE FARM SPA (IT) | 2020-07-22 | — | — | EP | disclosed |
| US-20200199129-A1 | PYRAZOLOPYRIMIDINE DERIVATIVES, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION FOR USE IN PREVENTING OR TREATING CANCER, AUTOIMMUNE DISEASE AND BRAIN DISEASE CONTAINING THE SAME AS AN ACTIVE INGREDIENT | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2020-06-25 | — | — | US | disclosed |
| US-20200199129-A1 | PYRAZOLOPYRIMIDINE DERIVATIVES, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION FOR USE IN PREVENTING OR TREATING CANCER, AUTOIMMUNE DISEASE AND BRAIN DISEASE CONTAINING THE SAME AS AN ACTIVE INGREDIENT | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2020-06-25 | — | — | US | disclosed |
| EP-3497085-A1 | SULFONAMIDES AS GPR40- AND GPR120-AGONISTS | Dompé farmaceutici S.p.A. (IT) | 2019-06-19 | — | — | EP | disclosed |
| US-20190169142-A1 | SULFONAMIDES AS GPR40- AND GPR120-AGONISTS | DOMPÉ FARMACEUTICI S.P.A. (IT) | 2019-06-06 | — | — | US | disclosed |
| CN-109641852-A | Sulfonamides as GPR 40-and GPR 120-agonists | 东佩制药股份公司 | 2019-04-16 | — | — | CN | disclosed |
| WO-2018208132-A1 | PYRAZOLOPYRIMIDINE DERIVATIVES, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION FOR USE IN PREVENTING OR TREATING CANCER, AUTOIMMUNE DISEASE AND BRAIN DISEASE CONTAINING THE SAME AS AN ACTIVE INGREDIENT | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2018-11-15 | — | — | WO | disclosed |
| WO-2018029150-A1 | SULFONAMIDES AS GPR40- AND GPR120-AGONISTS | DOMPE' FARMACEUTICI S.P.A. (IT) | 2018-02-15 | — | — | WO | disclosed |
| EP-3281937-A1 | SULFONAMIDES AS GPR40- AND GPR120-AGONISTS | Dompé farmaceutici S.p.A. (IT) | 2018-02-14 | — | — | EP | disclosed |
| EP-3046156-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT, AND ILLUMINATION DEVICE AND DISPLAY DEVICE EACH COMPRISING THE ELEMENT | Konica Minolta Holdings, Inc. (JP) | 2016-07-20 | — | — | EP | disclosed |
| EP-2453496-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT, NOVEL COMPOUND, LIGHTING DEVICE AND DISPLAY DEVICE | Konica Minolta Holdings, Inc. (JP) | 2012-05-16 | — | — | EP | disclosed |
| US-7183278-B1 | Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-02-27 | — | — | US | disclosed |
| EP-1134214-A1 | PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD. (JP) | 2001-09-19 | — | — | EP | disclosed |
| EP-0103541-B1 | ANTHRAQUINONE DYES, THEIR PREPARATION AND USE | CIBA-GEIGY AG (CH) | 1989-07-19 | — | — | EP | disclosed |
| US-4501592-A | Anthraquinone dyes, process for their preparation, and use thereof | CIBA-GEIGY CORPORATION (US) | 1985-02-26 | — | — | US | disclosed |
| EP-0103541-A2 | Anthraquinone dyes, their preparation and use | CIBA-GEIGY AG (CH) | 1984-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190169142-A1 | SULFONAMIDES AS GPR40- AND GPR120-AGONISTS | GPR119, GPR88, GPR84 | LTA4H 1061/4885TSHR 267/4885MAOA 4703/4885 |
| US-11084824-B2 | Pyrazolopyrimidine derivatives, preparation method thereof, and pharmaceutical composition for use in preventing or treating cancer, autoimmune disease and brain disease containing the same as an active ingredient | BTK, SYK, LCK | LTA4H 3471/4885TSHR 2632/4885MAOA 741/4885 |
| US-20200199129-A1 | PYRAZOLOPYRIMIDINE DERIVATIVES, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION FOR USE IN PREVENTING OR TREATING CANCER, AUTOIMMUNE DISEASE AND BRAIN DISEASE CONTAINING THE SAME AS AN ACTIVE INGREDIENT | BTK, SYK, LCK | LTA4H 3471/4885TSHR 2632/4885MAOA 741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.