Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11083127 | 0.80 | LTA4H (0.50) | PPARGST14MEN1KMT2ANPC1 | |
| SCHEMBL5028191 | 0.78 | LTA4H (0.52) | PPARGMEN1KMT2ANPC1RAB9A | |
| SCHEMBL8126114 | 0.77 | MAOA (0.59) | BACE1PPARGSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9680517 | 0.76 | ST14 (0.48) | PPARGST14MEN1KMT2ANPC1 | |
| SCHEMBL21085645 | 0.72 | LTA4H (0.62) | PPARGSLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL17294399 | 0.71 | MEN1 (0.41) | BACE1PDE4AST14MEN1KMT2A | |
| SCHEMBL217345 | 0.71 | MEN1 (0.62) | BACE1PPARGSLC6A4MEN1KMT2A | |
| SCHEMBL10605236 | 0.70 | TEAD4 (0.61) | MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL730661 | 0.70 | SLC6A2 (0.53) | PDE4ASLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL31238589 | 0.70 | ALDH1A1 (0.69) | MEN1KMT2ANPC1RAB9ANLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112942-A | Copolymers, aromatic diamine with alkyl substituents and phenoxy substituted aromatic diamine, resistance to stess cracking | ETHYL CORPORATION (US) | 1992-05-12 | — | — | US | disclosed |