Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9682901 | 0.90 | MAPT (0.43) | HDAC8MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL20715674 | 0.87 | HDAC8 (0.42) | HDAC8MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL9683129 | 0.86 | MAPT (0.47) | HDAC8MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL17149351 | 0.84 | KMT2A (0.44) | MAPTL3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL3235742 | 0.83 | SMN1; SMN2 (0.47) | MAPTMEN1KMT2AAPP | |
| SCHEMBL9681343 | 0.81 | HDAC3 (0.44) | MAPTL3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL17152742 | 0.80 | KCNQ3 (0.44) | MAPTL3MBTL1MEN1KMT2AEGFR | |
| SCHEMBL16044561 | 0.77 | AGER (0.56) | MAPTL3MBTL1MEN1KMT2AEGFR | |
| SCHEMBL9681871 | 0.77 | MAPT (0.43) | MAPTL3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL11569274 | 0.77 | ALDH1A1 (0.49) | MAPTL3MBTL1MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128359-A | Benzimidazole and azabenzimidazole derivatives which are thromboxane receptor antagonists, their methods of preparation | LABORATOIRES UPSA (FR) | 1992-07-07 | — | — | US | disclosed |
| US-5124336-A | Cardiovascular disorders | LABORATOIRES UPSA (FR) | 1992-06-23 | — | — | US | disclosed |