Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 3/20 | 0.36 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | UGCG | Q16739 | 1/20 | 0.34 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.32 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5411257 | 0.77 | ACHE (0.45) | ACHEPPARGAGTR1AGTR2PRKAG1 | |
| SCHEMBL9682387 | 0.76 | AGTR1 (0.43) | ACHEPPARGAGTR1AGTR2PTPN5 | |
| SCHEMBL5411252 | 0.71 | AGTR1 (0.43) | ACHEPPARGAGTR1AGTR2PRKAG1 | |
| SCHEMBL214 | 0.67 | PPARG (0.56) | PPARGAGTR1AGTR2 | |
| SCHEMBL9683668 | 0.67 | ACHE (0.58) | ACHEPPARGAGTR1AGTR2PRKAG1 | |
| SCHEMBL2692039 | 0.66 | PPARG (0.53) | ACHEPPARGAGTR1AGTR2PTPN5 | |
| SCHEMBL7649207 | 0.65 | ACHE (0.47) | ACHEPPARGAGTR1AGTR2PRKAG1 | |
| SCHEMBL4253889 | 0.65 | HSD17B10 (0.58) | ACHEPPARGAGTR1AGTR2ESR2 | |
| SCHEMBL9402468 | 0.65 | ACHE (0.44) | ACHEPPARGAGTR1AGTR2PRKAG1 | |
| SCHEMBL8298331 | 0.65 | ACHE (0.44) | ACHEPPARGAGTR1AGTR2ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128355-A | Hypotensive | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-07-07 | — | — | US | disclosed |