Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.46 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.46 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9682211 | 1.00 | KMT2A (0.54) | KMT2AKDM4ESMN1; SMN2PDE4BL3MBTL1 | |
| SCHEMBL23690433 | 0.86 | L3MBTL1 (0.55) | KMT2AKDM4ESMN1; SMN2PDE4BL3MBTL1 | |
| SCHEMBL18670699 | 0.82 | CYP2D6 (0.52) | KMT2AKDM4ESMN1; SMN2L3MBTL1POLB | |
| SCHEMBL3704563 | 0.81 | KDM4E (0.54) | KMT2AKDM4ESMN1; SMN2CA1CA2 | |
| SCHEMBL2818992 | 0.81 | KDM4E (0.54) | KMT2AKDM4ESMN1; SMN2CA1CA2 | |
| SCHEMBL29236452 | 0.81 | TOP2A (0.51) | KMT2AKDM4ESMN1; SMN2POLBMEN1 | |
| SCHEMBL9682217 | 0.80 | AKR1B10 (0.46) | KMT2AKDM4EPOLBMEN1GLA | |
| SCHEMBL11987691 | 0.80 | L3MBTL1 (0.57) | KMT2AKDM4ESMN1; SMN2PDE4BL3MBTL1 | |
| SCHEMBL9682234 | 0.80 | ALDH1A1 (0.42) | KMT2AKDM4ESMN1; SMN2POLBMEN1 | |
| SCHEMBL9682243 | 0.80 | ALDH1A1 (0.42) | KMT2AKDM4ESMN1; SMN2POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117986188-A | Preparation method of 9-alkenyl substituted acridine derivative | 郑州原理生物科技有限公司 | 2024-05-07 | — | — | CN | disclosed |
| US-5089377-A | Acridin-9-yl acrylates | ASAHI DENKA KOGYO K.K. (JP) | 1992-02-18 | — | — | US | disclosed |
| US-4985564-A | Acridine compound and photopolymerizable composition using the same | HITACHI CHEMICAL CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |