Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 3/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9682243 | 1.00 | ALDH1A1 (0.42) | ALDH1A1MAPK1KDM4EMAPTGLA | |
| SCHEMBL29236452 | 0.82 | TOP2A (0.51) | ALDH1A1MAPK1KDM4EMAPTGLA | |
| SCHEMBL9682217 | 0.82 | AKR1B10 (0.46) | ALDH1A1MAPK1KDM4EGLAPOLB | |
| SCHEMBL9683489 | 0.81 | LMNA (0.57) | ALDH1A1MAPK1KDM4EPOLBLMNA | |
| SCHEMBL9682780 | 0.81 | AKR1B10 (0.48) | ALDH1A1MAPK1KDM4EMAPTLMNA | |
| SCHEMBL9682777 | 0.81 | AKR1B10 (0.48) | ALDH1A1MAPK1KDM4EMAPTLMNA | |
| SCHEMBL9682795 | 0.80 | KMT2A (0.54) | ALDH1A1MAPK1KDM4EGLAPOLB | |
| SCHEMBL9682211 | 0.80 | KMT2A (0.54) | ALDH1A1MAPK1KDM4EGLAPOLB | |
| SCHEMBL2818992 | 0.74 | KDM4E (0.54) | ALDH1A1KDM4EMAPTGLALMNA | |
| SCHEMBL3704563 | 0.74 | KDM4E (0.54) | ALDH1A1KDM4EMAPTGLALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089377-A | Acridin-9-yl acrylates | ASAHI DENKA KOGYO K.K. (JP) | 1992-02-18 | — | — | US | disclosed |