Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 3/20 | 0.38 |
| ▸ | S100A4 | P26447 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9680412 | 0.82 | KMT2A (0.34) | PDGFRBTDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL9680365 | 0.82 | PBRM1 (0.35) | ALDH1A1CYP3A4PTPRCCES1MEN1 | |
| SCHEMBL9682041 | 0.82 | KDM4E (0.42) | PDGFRBALDH1A1S100A4MEN1KMT2A | |
| SCHEMBL9682834 | 0.79 | PDPK1 (0.39) | DAOMALT1 | |
| SCHEMBL9682156 | 0.78 | ALDH1A1 (0.38) | TDP1ALDH1A1CYP3A4PTPRCS100A4 | |
| SCHEMBL9682129 | 0.76 | ALDH1A1 (0.36) | TDP1ALDH1A1CYP3A4PTPRCS100A4 | |
| SCHEMBL8554186 | 0.75 | ATM (0.44) | ALDH1A1CYP3A4RAB9APOLBL3MBTL1 | |
| SCHEMBL9680374 | 0.74 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL9132454 | 0.73 | IGF1R (0.46) | — | |
| SCHEMBL9087110 | 0.73 | NPC1 (0.42) | TDP1ALDH1A1CYP3A4PTPRCS100A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112839-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-05-12 | — | — | US | disclosed |