Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18071831 | 0.80 | LOXL2 (0.52) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL17848998 | 0.78 | TMEM97 (0.43) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL1695076 | 0.75 | SMN1; SMN2 (0.66) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL20257166 | 0.75 | KCNH2 (0.50) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL3353131 | 0.75 | MEN1 (0.47) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL16722430 | 0.73 | MMP2 (0.48) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL4801300 | 0.73 | ALDH1A1 (0.60) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL1521016 | 0.72 | PTPRF (0.57) | MEN1KMT2ASMN1; SMN2APOBEC3AAPOBEC3G | |
| SCHEMBL25955581 | 0.72 | LOXL2 (0.43) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL10621456 | 0.70 | LMNA (0.50) | MEN1KMT2ASMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0509795-A2 | Carbamates of rapamycin | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-10-21 | — | — | EP | disclosed |
| US-5118678-A | Antibody inhibitors, antiinflammatory agents, fungicides, antitumor agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-06-02 | — | — | US | disclosed |