Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.50 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.44 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | OGT | O15294 | 1/20 | 0.39 |
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6647933 | 0.76 | ALDH1A1 (0.60) | CREBBPKDM4EALDH1A1SMYD3PDE3B | |
| SCHEMBL9682938 | 0.75 | TOP2A (0.51) | CREBBPKDM4EALDH1A1GRIA1SMYD3 | |
| SCHEMBL858860 | 0.73 | CREBBP (0.48) | CNR2CREBBPKDM4EALDH1A1SMYD3 | |
| SCHEMBL9368243 | 0.73 | ALDH1A1 (0.53) | CREBBPKDM4EALDH1A1SMYD3SYK | |
| SCHEMBL31357187 | 0.72 | CNR2 (0.70) | CNR2ALDH1A1IGFBP3NOS1 | |
| SCHEMBL5084291 | 0.72 | CNR2 (0.70) | CNR2ALDH1A1IGFBP3NOS1 | |
| SCHEMBL4404077 | 0.72 | CNR2 (0.64) | CNR2ALDH1A1IGFBP3NOS1 | |
| SCHEMBL9684816 | 0.71 | ALDH1A1 (0.55) | CREBBPKDM4EALDH1A1SMYD3ESR1 | |
| SCHEMBL9684965 | 0.71 | ALDH1A1 (0.55) | CREBBPKDM4EALDH1A1SMYD3PDE3B | |
| Water SCHEMBL27550989 | 0.71 | CNR2 (0.68) | CNR2ALDH1A1IGFBP3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147883-A | Antiischemic, stroke | ADIR ET COMPAGNIE (FR) | 1992-09-15 | — | — | US | disclosed |