Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.40 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5412117 | 0.79 | ATM (0.42) | HSD11B1PSIP1ATML3MBTL1CA1 | |
| SCHEMBL9242224 | 0.76 | MMP2 (0.35) | L3MBTL1CA1CA2CA7CA14 | |
| SCHEMBL7906867 | 0.76 | HSD11B1 (0.47) | HSD11B1PSIP1L3MBTL1GAAPKM | |
| SCHEMBL155621 | 0.75 | ALDH1A1 (0.32) | L3MBTL1ALDH1A1 | |
| SCHEMBL5158536 | 0.74 | PSIP1 (0.47) | HSD11B1PSIP1ATML3MBTL1GAA | |
| SCHEMBL33347 | 0.74 | ALDH1A1 (0.31) | L3MBTL1ALDH1A1 | |
| SCHEMBL27618765 | 0.74 | ALDH1A1 (0.31) | L3MBTL1ALDH1A1 | |
| SCHEMBL5013321 | 0.74 | ALDH1A1 (0.31) | L3MBTL1ALDH1A1 | |
| SCHEMBL20502359 | 0.73 | PSIP1 (0.45) | HSD11B1PSIP1ATML3MBTL1ALDH1A1 | |
| SCHEMBL28779828 | 0.71 | KIF11 (0.43) | ALDH1A1SMN1; SMN2KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091431-A | Hypotensive agents | SCHERING CORPORATION (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0330004-A1 | Nucleoside-type compounds as phosphodiesterase inhibitors | SCHERING CORPORATION (US) | 1989-08-30 | — | — | EP | disclosed |
| WO-1989007102-A1 | NULCEOSIDETYPE COMPOUNDS WHICH ARE PHOSPHODIESTERASE INHIBITORS | SCHERING CORPORATION (US) | 1989-08-10 | — | — | WO | disclosed |