Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 18/20 | 0.39 |
| ▸ | CA1 | P00915 | 7/20 | 0.39 |
| ▸ | CA4 | P22748 | 4/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9683134 | 0.63 | CA2 (0.51) | CA2CA1CA4CA12CA3 | |
| SCHEMBL9683128 | 0.61 | CA2 (0.55) | CA2CA1CA4CA12CA3 | |
| SCHEMBL11091893 | 0.61 | ALDH1A1 (0.43) | CA2CA12CA9LMNA | |
| SCHEMBL11094596 | 0.58 | HSD11B1 (0.41) | CA2CA1CA4CA12CA7 | |
| SCHEMBL11093373 | 0.58 | GRIA2 (0.43) | TSHR | |
| SCHEMBL11093428 | 0.58 | CA12 (0.45) | CA2CA4CA12CA7CA9 | |
| SCHEMBL11092352 | 0.58 | HTT (0.41) | LMNATSHR | |
| SCHEMBL11088008 | 0.57 | L3MBTL1 (0.45) | TSHR | |
| SCHEMBL9429371 | 0.57 | CA1 (0.52) | CA2CA1CA12CA7CA9 | |
| SCHEMBL8792296 | 0.57 | CA2 (0.54) | CA2CA1CA4CA12CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0479480-A2 | Substituted thieno(2,3-B)(1,4)thiazine-6-sulfonamides as antiglaucoma agents | MERCK & CO. INC. (US) | 1992-04-08 | — | — | EP | disclosed |